Demonstrates an efficient method for synthesizing benzimidazoles from aromatic amines and nitriles, implying broader applications in organic chemistry.
A visible-light-driven [3 + 2] annulation of N-substituted aromatic amines with nitriles has been developed, providing efficient access to benzimidazoles. The reaction proceeds under mild conditions with a broad substrate scope and good functional group tolerance. Mechanistic studies support a photoredox-catalyzed radical pathway.
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Jiang et al. (2026) studied this question.
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