What question did this study set out to answer?

The aim is to evaluate ECG changes in children with transfusion-dependent β-thalassemia and relate them to serum ferritin and chelation regimens.

Evaluation of electrocardiogram changes in children with transfusion-dependent β-thalassemia

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Cross-sectional study evaluates ECG abnormalities in pediatric β-TDT, highlighting need for routine screening.

The aim is to evaluate ECG changes in children with transfusion-dependent β-thalassemia and relate them to serum ferritin and chelation regimens.
Conducted a cross-sectional study with 120 pediatric β-TDT patients aged 2-18 years.
Performed 12-lead ECG and echocardiography to assess cardiac function.
Collected data on serum ferritin levels and transfusion history.
ECG abnormalities found in 55.8% of patients.
Positive correlation between P-wave dispersion and serum ferritin, especially above 5000 ng/ml.
Prolonged QRS duration was seen in 42% of children under 10 years compared to 10% of older children.

Adel et al. (2026) studied this question.

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