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Observational study links anti-nephrin autoantibodies with disease activity in minimal change disease, suggesting a potential noninvasive biomarker.
Anti-nephrin autoantibodies are associated with disease activity in MCD, exhibit an IgG4-predominant subclass, and are accompanied by a Th2-skewed cytokine profile. These findings suggest their potential as a noninvasive biomarker, warranting further prospective studies to validate their clinical utility.
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Guo et al. (2026) studied this question.
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