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April 24, 2026JMIR mhealth and uhealthOpen Access

Effectiveness of Mobile Health Interventions in Pediatric Cancer: Systematic Review and Meta-Analysis of Randomized Controlled Trials

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Authors

HYHuilu YaoYWYiting WenHWHongxiu Wang

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Overview

Systematic review demonstrates mHealth reduces infections and improves outcomes in pediatric cancer.

Key Points

  • This study aims to summarize the effectiveness of mobile health interventions for pediatric cancer in comparison to usual care.
  • Conducted a systematic search of 14 databases for randomized controlled trials on mHealth for pediatric patients with cancer.
  • Two reviewers screened studies, extracted data, assessed bias risk, and graded evidence quality.
  • Performed a meta-analysis using RevMan 5.4 and Stata 15.
  • mHealth interventions significantly reduced infection rates (OR 0.25, P =.002) and PICC complications (OR 0.16, P <.001).
  • Improved quality of life (SMD 1.34, P =.03), self-management ability (SMD 6.39, P =.01), and treatment adherence (OR 2.83, P =.003).
  • No significant effect observed on PICC catheter displacement (OR 0.44, P =.13) or health knowledge (SMD 4.44, P =.20).

Cite This Study

Yao et al. (2026) studied this question.

synapsesocial.com/papers/69eb0bfa553a5433e34b56c3https://doi.org/10.2196/86836
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Also Consider

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  4. 4Effectiveness of Digital and Remote Health Interventions in Pediatric Populations From Underserved or Rural Areas: A Systematic Review of Randomized Controlled Trials2026 · 2 citations
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