What does this research mean for the field?

Patient-facing mHealth applications produce large, significant improvements in quality of life and medication adherence for adult cancer patients undergoing chemotherapy. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the effectiveness of patient-facing mobile health applications on quality of life and treatment adherence in adult cancer patients undergoing active chemotherapy.

August 22, 2026Journal of Oncology Pharmacy Practice

Patient-facing mobile health applications for quality of life and treatment adherence during cancer chemotherapy: A systematic review and meta-analysis

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Authors

GPG Hari PrakashJSS Academy of Higher Education and Research SDSunil Kumar DoddaiahJSS Academy of Higher Education and Research TDTejaswini B. DarukaradhyaM S Ramaiah University of Applied Sciences

Discussion

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Implication

Systematic review and meta-analysis demonstrates that mobile health apps significantly improve quality of life during cancer chemotherapy, indicating strong utility in oncology care.

Key Points

To evaluate the effectiveness of patient-facing mobile health applications on quality of life and treatment adherence in adult cancer patients undergoing active chemotherapy.
Conducted a systematic search across seven databases from January 2014 to June 2026.
Included 22 studies (N = 3,505 participants; 14 RCTs, 5 quasi-experimental, 1 cluster-RCT, 1 protocol) across 11 countries assessing patient-facing mHealth tools reporting QoL or adherence.
Pooled random-effects meta-analysis demonstrated a statistically significant, large improvement in quality of life favoring mHealth interventions (Hedges’ g = 0.981, 95% CI: 0.336 to 1.626, P = 0.003; k = 9, n = 939).
Statistically significant improvements in quality of life were reported in 17 of 19 studies (89%), and medication adherence significantly improved across five studies, with moderate overall certainty of evidence (GRADE).

Cite This Study

Prakash et al. (2026) studied this question.

synapsesocial.com/papers/6a898131ca7ade938187f375 https://doi.org/10.1177/10781552261478233

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Implication

Systematic review and meta-analysis demonstrates that mobile health apps significantly improve quality of life during cancer chemotherapy, indicating strong utility in oncology care.

Patient-facing mobile health applications for quality of life and treatment adherence during cancer chemotherapy: A systematic review and meta-analysis

Discussion

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Implication

Key Points

Cite This Study

Patient-facing mobile health applications for quality of life and treatment adherence during cancer chemotherapy: A systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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