Is Unplanned Excision of Soft Tissue Sarcomas Associated with Worse Oncological Outcomes?—A Systematic Review and Meta-Analysis

Figure 1. Flowchart of our literature search and selection of relevant articles.

Figure 2. Forest plot of studies assessing risk ratios (RR) for five-year overall survival in patients with unplanned excisions and patients with planned excisions [4,8,10,12,14,15,18,21,23,24,25,26,30,31,32,34,36,39,42,43,44,46].

Figure 3. (A,B) Forest plot of (A) studies assessing risk ratios (RR) for five-year local recurrence-free survival in patients with unplanned excisions and patients with planned excisions and (B) studies assessing risk ratios (RR) for five-year local recurrence-free survival in patients with positive residual disease at re-excision and patients with negative residual disease at re-excision [3,8,10,11,12,13,16,17,24,25,27,28,29,30,31,32,33,35,37,38,39,40,41,42,43,44,47].

Figure 4. Forest plot of studies assessing risk ratios (RR) for five-year overall survival in patients that developed local recurrence and patients that did not develop local recurrence [8,19,22,45,48].

Figure 5. (A,B) Forest plot of studies assessing risk ratios (RR) for (A) amputation rate and (B) plastic reconstruction surgery rate in patients with unplanned excisions and patients with planned excisions [4,9,12,14,16,17,20,21,24,25,30,35,36,39,42,44].