Comparison of the efficacy of sublingual immunotherapy and prophylactic treatment with antihistamines on allergic rhinitis symptoms and quality of life in small and large Japanese cedar pollen dispersal years

Tatsuya Fujii; Seiichiro Kamimura; Keisuke Ishitani; Yoshiaki Kitamura

doi:10.2152/jmi.73.55

January 1, 2026The Journal of Medical InvestigationOpen Access

Comparison of the efficacy of sublingual immunotherapy and prophylactic treatment with antihistamines on allergic rhinitis symptoms and quality of life in small and large Japanese cedar pollen dispersal years

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Key Points

To compare the efficacy of sublingual immunotherapy (SLIT) and antihistamines in managing allergic rhinitis (AR) symptoms and enhancing quality of life during Japanese cedar pollen dispersal seasons.
Conducted over different dispersal years of Japanese cedar pollen
Compared symptom relief with SLIT and prophylactic antihistamine treatment
Measured quality of life improvements during high pollen periods.
SLIT demonstrated greater effectiveness in reducing allergic rhinitis symptoms compared to antihistamines during large JC pollen seasons
Improved quality of life was noted in patients receiving SLIT during these periods.

Implication

Compares symptom relief in allergic rhinitis using sublingual immunotherapy and antihistamines, indicating better outcomes during high pollen seasons.

Abstract

These findings suggested that JC pollen SLIT was more effective in suppressing AR symptoms than prophylactic treatment with antihistamines, resulting in improved QOL during the large JC pollen dispersal season. J. Med. Invest. 73 : 55-61, February, 2026.

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Fujii et al. (2026) studied this question.

synapsesocial.com/papers/69ec593e88ba6daa22dab407 https://doi.org/10.2152/jmi.73.55

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Comparison of the efficacy of sublingual immunotherapy and prophylactic treatment with antihistamines on allergic rhinitis symptoms and quality of life in small and large Japanese cedar pollen dispersal years

Key Points

Implication

Abstract

Discussion

Cite This Study

Comparison of the efficacy of sublingual immunotherapy and prophylactic treatment with antihistamines on allergic rhinitis symptoms and quality of life in small and large Japanese cedar pollen dispersal years

Key Points

Implication

Abstract

Discussion

Cite This Study

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