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This study aims to evaluate the protective effect of Panax ginseng against bisphenol A-induced testicular toxicity in rats.

Protective effects of panax ginseng against bisphenol a-induced testicular toxicity in rats

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Randomized trial evaluates panax ginseng's protective role in reducing testicular damage from bisphenol A in rats, indicating potential therapies.

This study aims to evaluate the protective effect of Panax ginseng against bisphenol A-induced testicular toxicity in rats.
Thirty-two Wistar Albino rats were divided into four groups: Control, PG, BPA, and BPA + PG.
BPA (50 mg/kg/day) and PG (100 mg/kg/day) were administered orally for 6 weeks.
Histopathological examination of testicular tissues was conducted to assess damage.
BPA increased serum total oxidant status and decreased antioxidant status (p < 0.001).
PG treatment significantly improved oxidative and inflammatory markers, restoring androgen receptor levels (p = 0.014).
Histopathological analysis showed reduced degeneration and increased spermatozoa in the BPA + PG group compared to BPA group.

Dörücü et al. (2026) studied this question.

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Randomized trial evaluates panax ginseng's protective role in reducing testicular damage from bisphenol A in rats, indicating potential therapies.