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April 26, 2026Japanese Journal of Large Animal ClinicsOpen Access

A case of enzootic bovine leukosis with overt lymphocytosis in a Japanese Black cow

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Authors

STS. TakezawaKYK. YoshidaKWK. Watanabe

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Overview

Randomized trial investigates enzootic bovine leukosis in a Japanese Black cow, indicating the importance of multiple diagnostic tests.

Key Points

  • The aim is to investigate the presence of enzootic bovine leukosis (EBL) and lymphocytosis in a Japanese Black cow showing relevant clinical signs.
  • Clinical examination and blood tests assessed lymphocyte counts and BLV antibodies.
  • B cell clonality was determined using IgH-PCR and inverse PCR methods.
  • Histopathological analysis of affected tissues was conducted.
  • The cow exhibited significant lymphocytosis (69,843/μL) and was positive for BLV antibodies.
  • Histological evaluation revealed B cell lymphomas in multiple tissues, confirming EBL.
  • Monitoring various diagnostic tests improved the sensitivity of EBL diagnosis.

Cite This Study

Takezawa et al. (2024) studied this question.

synapsesocial.com/papers/69edaafc4a46254e215b3446https://doi.org/10.4190/jjlac.15.183
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