Key result
Unhealthy lifestyle and socioeconomic patterns in obese adults linked to ~11-fold higher CVD risk.
Why the study?
Cardiovascular disease risk factors frequently co-occur within specific identifiable patterns, prompting the need to examine risk associations across lifestyle and socioeconomic clusters in adults with obesity.
Do specific clusters of lifestyle and socioeconomic factors associate with higher cardiovascular disease risk in middle-aged and older US adults with obesity?
Population
3074 middle-aged and older US adults with obesity
Comparison
Clusters of lifestyle and socioeconomic factors vs health reference class
Design
Cross-sectional analysis of four biennial cycles of National Health and Nutrition Examination Survey data
Authors
Loading...
Should not yet change CVD risk stratification in obese men; leaves open whether lifestyle-socioeconomic clusters are causal or modifiable.
Cross-Sectional (n=3,074)
Do specific clusters of lifestyle and socioeconomic factors associate with higher cardiovascular disease risk in middle-aged and older US adults with obesity?
Effect estimate: OR 11.50 (95% CI 3.50-27.78)
Socioeconomic status and lifestyle choices cluster together to significantly impact cardiovascular disease risk in middle-aged and older adults with obesity.
Xu et al. (2026) conducted a cross-sectional in Obesity and cardiovascular disease risk (n=3,074). Unhealthy lifestyle and socioeconomic patterns (Classes 2-4) vs. Health reference class (Class 1) was evaluated on Cardiovascular disease risk (OR 11.50, 95% CI 3.50-27.78). Unhealthy lifestyle and socioeconomic patterns in obese adults were associated with higher cardiovascular disease risk compared to a reference class (highest risk OR 11.50; 95% CI 3.50-27.78).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: