Addressing Multidrug-resistant Bacterial Infections with Iridium-based Theragnostic Agents

Rama Karn; Mahesmita Sahoo; Sayantani Biswas; Suravi Chauhan; Ajay Kumar Nag; Soham Basu; Srikanta Patra; Debasis Manna

doi:10.1039/d6md00120c

January 1, 2026RSC Medicinal Chemistry

Addressing Multidrug-resistant Bacterial Infections with Iridium-based Theragnostic Agents

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Key Points

This research aims to explore the effectiveness of iridium-based theragnostic agents in tackling multidrug-resistant bacterial infections.
Study assessing the efficacy of iridium-based agents against specific bacterial strains.
In vitro testing of transition-metal complexes for their antimicrobial activities.
Analysis of fluorescence properties in relation to their mechanism of action.
Iridium-based agents displayed significant antimicrobial activity against targeted multidrug-resistant strains.
Enhanced fluorescence properties correlated with increased effectiveness in bacterial eradication.

Implication

Investigates iridium-based agents against multidrug-resistant bacterial infections, suggesting novel treatment approaches.

Abstract

Effective strategies are essential for addressing bacterial infections caused by antimicrobial resistance (AMR). The increasing interest in transition-metal complexes stems from their fluorescence properties and diverse mechanisms of action against...

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Cite This Study

Karn et al. (2026) studied this question.

synapsesocial.com/papers/69edabdf4a46254e215b3b1f https://doi.org/10.1039/d6md00120c

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Addressing Multidrug-resistant Bacterial Infections with Iridium-based Theragnostic Agents

Key Points

Implication

Abstract

Discussion

Cite This Study

Addressing Multidrug-resistant Bacterial Infections with Iridium-based Theragnostic Agents

Key Points

Implication

Abstract

Discussion

Cite This Study

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