What question did this study set out to answer?

The research aims to identify risk factors associated with adverse circulatory and respiratory events during esophageal endoscopic submucosal dissection under dexmedetomidine-based sedation.

April 26, 2026Korean Journal of Gastroenterology0 citationsOpen Access

Risk Factors for Adverse Circulatory and Respiratory Events in Patients Undergoing Esophageal Endoscopic Submucosal Dissection Under Dexmedetomidine-Based Sedation

KMKenshi MatsunoKumamoto University Hospital HMHideaki MiyamotoKumamoto University STSayoko TayamaKumamoto University Hospital

Key Points

The research aims to identify risk factors associated with adverse circulatory and respiratory events during esophageal endoscopic submucosal dissection under dexmedetomidine-based sedation.
Analyzed the impact of protein nutritional index (PNI) on complication rates during ESD procedures.
Focused on elderly patients undergoing sedation for esophageal endoscopic submucosal dissection using dexmedetomidine.
Patients with lower protein nutritional index (PNI) had a higher likelihood of circulatory and respiratory complications.
Elderly patients were particularly at increased risk for such events during ESD.

Abstract

When performing ESD for ESCC under DEX-based sedation, special caution is needed for patients with lower PNI and the elderly, who are more likely to experience circulatory or respiratory complications.

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