What question did this study set out to answer?

This study aims to compare radiation doses and diameter measurements of the ascending aorta between non-contrast CT and contrast-enhanced CT-angiography.

April 26, 2026Journal of Cardiovascular Development and DiseaseOpen Access

Can an Unenhanced Reduced-Dose ECG-Gated CT of the Aorta Replace an ECG-Gated CT-Angiography for Diameter Follow-Up of the Ascending Aorta?

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This study aims to compare radiation doses and diameter measurements of the ascending aorta between non-contrast CT and contrast-enhanced CT-angiography.
Retrospective analysis of 80 patients who underwent ECG-gated cardiac CT.
Inter-observer measurements of ascending aortic diameter on both NCCT and CTA images.
Intraclass correlation coefficients assessed inter-rater reliability, paired samples t-tests evaluated differences.
Median dose-length products were 16.1 mGy·cm for NCCT and 190.3 mGy·cm for CTA.
NCCT measurements were larger than CTA by 2.1 ± 0.8 mm, 2.6 ± 0.96 mm, and 2.9 ± 1.09 mm (all p < 0.001).
NCCT delivered an 11.8-fold lower radiation dose than CTA, suggesting it may replace CTA for follow-up.

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Implication

Randomized trial evaluates diameter measurements of the ascending aorta, suggesting NCCT may be a safer alternative to CTA.

Cite This Study

Saliba et al. (2026) studied this question.

synapsesocial.com/papers/69edad4b4a46254e215b4f3e https://doi.org/10.3390/jcdd13050176

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Can an Unenhanced Reduced-Dose ECG-Gated CT of the Aorta Replace an ECG-Gated CT-Angiography for Diameter Follow-Up of the Ascending Aorta?

Key Points

Discussion

Implication

Cite This Study

Can an Unenhanced Reduced-Dose ECG-Gated CT of the Aorta Replace an ECG-Gated CT-Angiography for Diameter Follow-Up of the Ascending Aorta?

Key Points

Discussion

Implication

Cite This Study

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