Key result
Harmony valve implantation linked to iatrogenic RVOT-to-right coronary sinus communication in pulmonary stenosis.
Why the study?
Rapid adoption of self-expanding valve platforms in native right ventricular outflow tracts has led to unpredicted complications related to valve design and patient anatomy.
Case Report (n=1)
Highlights a rare but significant complication of Harmony valve implantation, specifically an iatrogenic communication between the RVOT and the right coronary sinus.
The use of self-expanding valve platforms in the setting of regurgitant native right ventricular outflow tracts is progressing rapidly, promising the potential of lifetime percutaneous therapy for some patients who previously had been committed to sternotomy with cardiopulmonary bypass surgery. These developments have been associated with some unpredicted complications whose aetiologies are now starting to develop into patterns which may be related to valve design as well as specific patient anatomic substrates. We report the case of an iatrogenic communication from the RVOT into the right coronary sinus by a Harmony valve in a patient whose original diagnosis was pulmonary stenosis with a small ventricular septal defect.
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Morgan et al. (2026) conducted a case report in Pulmonary stenosis with a small ventricular septal defect (n=1). Harmony valve implantation was evaluated on Iatrogenic communication from the RVOT into the right coronary sinus. Harmony valve implantation resulted in an iatrogenic communication from the right ventricular outflow tract into the right coronary sinus in a patient with pulmonary stenosis.
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