Why the study?
Does L-arginine improve impaired acetylcholine-induced and ischemic vasodilation of the forearm in patients with heart failure?
Does L-arginine improve impaired acetylcholine-induced and ischemic vasodilation of the forearm in patients with heart failure?
Defective endothelial function may contribute to impaired ischemic vasodilator capacity in heart failure.
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Endothelial dysfunction may limit ischemic vasodilation in HF; hypothesis-generating and should not yet change practice.
Our results suggest that defective endothelial function may contribute to impaired ischemic vasodilator capacity in HF.
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Hirooka et al. (1994) studied this question.
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