Why the study?
Does antiarrhythmic therapy or ICD placement reduce mortality and sudden cardiac death in patients at risk for sudden cardiac death?
Does antiarrhythmic therapy or ICD placement reduce mortality and sudden cardiac death in patients at risk for sudden cardiac death?
ICDs and beta-blockers are effective for preventing sudden cardiac death in high-risk patients, while antiarrhythmic drugs are generally reserved for adjunctive therapy to reduce ICD shocks or when ICDs are inappropriate.
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May support prioritizing beta-blockers and ICDs in high-risk patients; leaves open optimal class III adjunctive strategies.
Hilleman et al. (2001) studied this question.
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