What question did this study set out to answer?

This review aims to connect hallmarks of immunosenescence with potential therapeutic interventions to enhance immune function in aging.

Immunosenescence and Inflammaging: From Pathological Hallmarks to Rejuvenation Strategies

View Full Paper

Ask AI

Bookmark

Authors

Review synthesizes therapeutic strategies targeting immunosenescence in aging populations, suggesting implications for healthspan extension.

This review aims to connect hallmarks of immunosenescence with potential therapeutic interventions to enhance immune function in aging.
Synthesized emerging therapeutic strategies targeting specific hallmarks of immunosenescence.
Examined senotherapeutics for immune clearance of senescent cells and interventions for lymphocyte restoration.
Proposed a precision medicine framework to design combinatorial regimens.
Identified specific nodes in the immunosenescence network as intervention targets.
Highlighted the effectiveness of senotherapeutics in clearing cellular senescence.
Proposed metabolic-epigenetic strategies to rectify immune dysfunctions.

Hou et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Review synthesizes therapeutic strategies targeting immunosenescence in aging populations, suggesting implications for healthspan extension.