Demonstrates a highly diastereoselective cycloannulation in naphthalene synthesis, suggesting new pathways for complex molecule formation.
A highly diastereoselective (4 + 3)‐cycloannulation of in situ generated carbonyl ylides and 3‐aryl‐1‐(2‐(1‐arylvinyl)phenyl)prop‐2‐yn‐1‐ones enabled by silver catalysis is described. This study is the first to report the synthesis of naphthalenes with an oxa‐bridged motif using silver catalysis. The reaction's scope is broad and the oxa‐bridged naphthalene products were obtained in good to high yields and with excellent diastereoselectivities.
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Jaiswal et al. (2026) studied this question.
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