Optimisation of Supercritical CO2 Extraction of Phenolic Compounds from Tomato ( Solanum lycopersicum L.) Seeds Using Response Surface Methodology

Abderrahmane Tighrine; Anna Montefusco; Monica De Caroli; Marcello Salvatore Lenucci

doi:10.1093/jaoacint/qsag033

April 21, 2026Journal of AOAC International

Optimisation of Supercritical CO2 Extraction of Phenolic Compounds from Tomato ( Solanum lycopersicum L.) Seeds Using Response Surface Methodology

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Key Points

The study aims to optimize the extraction of phenolic compounds from tomato seeds using supercritical CO2 extraction.
Optimized extraction conditions using response surface methodology (RSM) based on pressure and co-solvent amounts.
Analysis of extracted compounds via HPLC-DAD-TOF to identify phenolic content.
Extraction yield and phenolic recovery were significantly influenced by pressure and co-solvent concentration.
Key phenolic compounds were identified, suggesting valuable by-products from tomato processing.

Implication

Study optimizes extraction yield of phenolic compounds from tomato seeds, suggesting improved sustainability in food processing.

Abstract

Optimized SC-CO2 extraction using RSM revealed that the factors most influencing oil extraction yield and the recovery of phenolic compounds were pressure and the quantity of co-solvents used. HPLC-DAD-TOF analysis putatively annotated the main phenolic compounds, thus emphasizing the sustainable valorization of by-products from tomato processing.

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Cite This Study

Tighrine et al. (2026) studied this question.

synapsesocial.com/papers/69eefde9fede9185760d4b77 https://doi.org/10.1093/jaoacint/qsag033

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Optimisation of Supercritical CO2 Extraction of Phenolic Compounds from Tomato ( Solanum lycopersicum L.) Seeds Using Response Surface Methodology

Key Points

Implication

Abstract

Discussion

Cite This Study

Optimisation of Supercritical CO2 Extraction of Phenolic Compounds from Tomato ( Solanum lycopersicum L.) Seeds Using Response Surface Methodology

Key Points

Implication

Abstract

Discussion

Cite This Study

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