C-Reactive Protein Adds to the Predictive Value of Total and HDL Cholesterol in Determining Risk of First Myocardial Infarction
Why the study?
Does baseline CRP level add to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction in apparently healthy men?
Population
Apparently healthy men
Comparison
Baseline C-Reactive Protein (CRP) level assessment vs Total and HDL cholesterol assessment alone
Design
Cohort
Authors
Discussion
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Member takes
Implication
May refine primary prevention risk assessment beyond lipids; hypothesis-generating without evidence that CRP modulation reduces MI.
Structured PICO
Does baseline CRP level add to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction in apparently healthy men?
P
Population
Apparently healthy men
I
Intervention
Baseline C-Reactive Protein (CRP) level assessment
C
Comparator
Total and HDL cholesterol assessment alone
O
Outcome
First myocardial infarctionhard clinical
Baseline CRP level adds predictive value to traditional lipid parameters for determining the risk of first myocardial infarction in healthy men.
Cite This Study
Ridker et al. (1998) studied this question.