July 1, 1984AJP Endocrinology and Metabolism
Measurement of total and organ-specific norepinephrine kinetics in humans
Population
Humans
Design
Other
Authors
Discussion
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Member takes
Implication
Challenges classic organ hierarchies for norepinephrine spillover; leaves open whether pulmonary release alters sympathetic assessment in cardiovascular disease.
Structured PICO
P
Population
Humans
I
Intervention
Radiotracer techniques for measuring organ-specific norepinephrine spillover rate
O
Outcome
Organ-specific norepinephrine spillover ratessurrogate
Radiotracer techniques reveal that the lungs are the primary source of norepinephrine release to plasma in humans, accounting for 40% of total release.
Cite This Study
Esler et al. (1984) studied this question.