August 25, 2010Circulation Heart Failure125 citations
View Full PaperSurvival After Cardiac Transplantation in Patients With Hypertrophic Cardiomyopathy
Structured PICO
Does heart transplantation provide comparable survival in patients with hypertrophic cardiomyopathy compared to those with non-HCM cardiovascular diseases?
P
Population
Patients who undergo heart transplantation in the United States, including patients with hypertrophic cardiomyopathy (HCM) and non-HCM cardiovascular diseases.
I
Intervention
Heart transplantation for hypertrophic cardiomyopathy
C
Comparator
Heart transplantation for non-HCM cardiovascular diseases
O
Outcome
Survival after transplanthard clinical
Survival after heart transplantation for hypertrophic cardiomyopathy is comparable to or potentially better than survival for other cardiovascular diseases.
Abstract
HCM patients compose a small subset (1%) of the overall population of patients who undergo heart transplantation in the United States. Nonetheless, survival after transplant among HCM patients is comparable to that of patients transplanted for non-HCM cardiovascular diseases, with possible enhanced survival over time.