Why the study?
Does renal sympathetic denervation improve office and ambulatory blood pressure in patients with resistant hypertension?
Does renal sympathetic denervation improve office and ambulatory blood pressure in patients with resistant hypertension?
Renal sympathetic denervation improves both office and ambulatory blood pressure in true resistant hypertension, but only office blood pressure in pseudoresistant hypertension.
May support ambulatory BP benefit with RDN only in true resistant hypertension; hypothesis-generating and requires RCTs before practice change.
RDN reduced office BP and improved relevant aspects of ambulatory BP monitoring, commonly linked to high cardiovascular risk, in patients with true-treatment resistant hypertension, whereas it only affected office BP in pseudoresistant hypertension.
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Mahfoud et al. (2013) studied this question.
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