Why the study?
Does low gradient, low flow, or low ejection fraction predict late mortality in high-risk patients with severe aortic stenosis undergoing TAVR?
Does low gradient, low flow, or low ejection fraction predict late mortality in high-risk patients with severe aortic stenosis undergoing TAVR?
In contradiction to previous reports, low gradient, rather than low flow or low ejection fraction, independently predicts late mortality after TAVR in high-risk patients with severe aortic stenosis.
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LG was associated with late mortality after TAVR in severe AS; challenges prior reports on LF/LEF and leaves open need for prospective validation.
Patients with HG and those with NF-LG have low one-year mortality rates following TAVR, whereas those with classical LF-LG and LEF and those with paradoxical LF-LG and NEF have high and intermediate risk of mortality, respectively. In contradiction to previous reports, LG but not LF or LEF is an independent predictor of late mortality in high-risk patients with severe AS undergoing TAVR.
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Abramowitz et al. (2017) studied this question.
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