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January 15, 2009Cardiovascular ResearchOpen Access

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

Sashwati Roy Savita Khanna Syed-Rehan A. Hussain Sabyasachi Biswas Ali Azad Cameron Rink Surya Gnyawali Shani Shilo Gerard J. Nuovo Chandan K. Sen

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Abstract

This work constitutes the first report describing changes in miR expression in response to IR in the mouse heart, showing that miR-21 regulates MMP-2 expression in CFs of the infarct zone via a PTEN pathway.

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Roy et al. (2009) studied this question.

synapsesocial.com/papers/69effb364f6a06657c21e370 https://doi.org/10.1093/cvr/cvp015

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