Does DOAC reduce dementia risk compared with warfarin in patients with atrial fibrillation?
DOACs are associated with a significantly lower risk of dementia compared to warfarin in patients with atrial fibrillation, especially in Asian populations.
The use of DOAC in AF significantly reduces dementia risk compared with warfarin, particularly in Asian patients. The possible reversal of this effect with increasing age merits further randomized trials with long-term follow-up. (Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial Fibrillation: A Systematic Review and Meta-Analysis; CRD42022365634).
Fong et al. (Tue,) studied this question.
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