Why the study?
Does chronic atrial fibrillation increase the risk of stroke with increasing age in men and women?
Population
5,184 men and women in the Framingham Heart Study
Design
Cohort
Follow-up
30 years
Authors
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AF-associated strokes rise with age; extends age-stratified epidemiology but observational data leave causal and therapeutic implications open.
Does chronic atrial fibrillation increase the risk of stroke with increasing age in men and women?
Atrial fibrillation is a major contributor to stroke risk at all ages, with the proportion of strokes attributable to this arrhythmia increasing significantly in the elderly.
Philip A. Wolf (1987) studied this question.