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April 28, 2026Frontiers in Veterinary ScienceOpen Access

Protective effect of Chlorella vulgaris on sub-chronic hepatic and testicular toxicity induced by acetamiprid in rats

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Authors

HFHuda M. FoudaKafrelsheikh UniversityTYT.A. YosefKafrelsheikh UniversitySESamia M. Abd El-RheemAlexandria University

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Implication

Randomized trial investigates the protective effect of Chlorella vulgaris on liver and testis toxicity in rats, suggesting its potential benefits against harmful insecticides.

Key Points

  • This study aims to evaluate the protective effects of Chlorella vulgaris against hepatic and testicular toxicity induced by acetamiprid in rats.
  • Thirty-two male rats were divided into four groups, with one group receiving acetamiprid and another group receiving Chlorella vulgaris.
  • All treatments were administered daily by oral gavage for 9 weeks.
  • Samples were collected for biochemical analysis, comet assay, and histopathological examination post-euthanasia.
  • The ACMP group showed lower sperm characteristics and reduced enzymatic antioxidants (p<0.05).
  • ACMP administration elevated malondialdehyde levels and increased DNA damage significantly compared to the CTRL group (p<0.01).
  • C. vulgaris co-administration restored parameters to levels comparable to the CTRL group, indicating its protective effect.

Cite This Study

Fouda et al. (2026) studied this question.

synapsesocial.com/papers/69f04d9f727298f751e71e9ehttps://doi.org/10.3389/fvets.2026.1782904
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