Concise review examines SIRT7's impact on aging mechanisms, highlighting its deacetylase activity and genomic stability.
This concise review examines the molecular mechanisms underlying SIRT7's role in biological aging, with emphasis on its nucleolar deacetylase activity, rDNA repeat stabilization, and intersection with canonical hallmarks of aging. Evidence is stratified by confidence level across in vitro, rodent, and human model systems.
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Alice Frolov (2026) studied this question.
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