Does surgical castration eliminate the Brugada-type ECG pattern in patients with asymptomatic Brugada syndrome?
Surgical castration led to the disappearance of the Brugada-type ECG pattern in two asymptomatic patients, suggesting a potential link between testosterone and Brugada syndrome manifestations.
We describe two cases of asymptomatic Brugada syndrome that displayed a persistent ECG manifestation, but in which the typical ECG pattern disappeared following surgical castration for prostate cancer. These facts suggest a possible association between manifestation of the Brugada-type ECG pattern and testosterone.
Matsuo et al. (Mon,) studied this question.