February 22, 2005Circulation
Troponin Elevation After Percutaneous Coronary Intervention Directly Represents the Extent of Irreversible Myocardial Injury
Why the study?
Does troponin elevation after PCI correlate with the extent of irreversible myocardial injury on delayed-enhancement MRI in patients undergoing PCI?
Population
50 patients undergoing percutaneous coronary intervention (PCI), mean age 64+/-12 years.
Design
Cohort
Follow-up
24 hours (subset at median 8 months)
Authors
Discussion
Loading...
Member takes
Implication
Troponin rise may mark new irreversible injury post-PCI; leaves open effects on prognosis and management.
Structured PICO
Does troponin elevation after PCI correlate with the extent of irreversible myocardial injury on delayed-enhancement MRI in patients undergoing PCI?
P
Population
50 patients undergoing percutaneous coronary intervention (PCI), mean age 64+/-12 years.
I
Intervention
Delayed-enhancement MRI and cardiac troponin I measurements before and 24 hours after PCI.
O
Outcome
Correlation between postprocedural changes in cardiac troponin I and the incidence and extent of new irreversible myocardial injury on delayed-enhancement MRI.surrogate
Postprocedural troponin I elevation after PCI directly correlates with the extent of new irreversible myocardial injury as quantified by delayed-enhancement MRI.
Cite This Study
Selvanayagam et al. (2005) studied this question.