The aim is to explore the role of nitrogen-containing heterocycles in pharmaceuticals and their therapeutic significance.
Review of nitrogen-containing FDA-approved drugs in 2025
Analysis of synthetic pathways for N-Hets
Assessment of therapeutic applications of these compounds
Nitrogen-containing heterocycles are key structural motifs in over 85% of active small molecules
N-Hets demonstrate versatility in pharmaceutical development
Significant potential for therapeutic applications identified
Abstract
Nitrogen-containing heterocycles (N-Hets) are among the most prevalent and versatile structural motifs in pharmaceuticals, serving as key scaffolds in over 85% of biologically active small molecules.