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April 29, 2026Journal of Microbiology and Biotechnology0 citations

Crystal Structure of Periplasmic Domain of YejM from Klebsiella pneumoniae

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KJKyoung Ho JungChung-Ang UniversityHHHyun Ji HaChung-Ang UniversityMSMina SonChung-Ang University

Key Points

  • This research investigates the structural features of YejM in Klebsiella pneumoniae to understand its functional role.
  • Determined crystal structure of YejM's periplasmic domain from Klebsiella pneumoniae.
  • Conducted comparative analyses within Gram-negative bacteria.
  • Characterized the molecular mechanism of YejM regulation of outer membrane lipid homeostasis.
  • Provided structural insights supporting evolutionary conservation of YejM functions.

Abstract

, supporting a conserved functional role for YejM across species. These findings extend current structural knowledge of YejM to an important opportunistic pathogen and reinforce the view that the molecular mechanism underlying YejM-mediated regulation of outer membrane lipid homeostasis is evolutionarily conserved among Gram-negative bacteria.

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Cite This Study

Jung et al. (2026) studied this question.

synapsesocial.com/papers/69f154e0879cb923c4945324https://doi.org/10.4014/jmb.2026.02020
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