Observational study highlights progressive renal failure in IgA-dominant MPGN, suggesting urgent need for better treatment approaches.
IgA-dominant idiopathic MPGN exhibits an aggressive course with poor renal outcomes compared to typical IgAN. The absence of identifiable secondary causes and high progression to ESKD highlight its severity and the urgent need for targeted research to better understand its pathogenesis and refine treatment approaches.
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Elahi et al. (2026) studied this question.
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