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April 29, 2026Open Access

Field Evaluation of a Point-of-Care Circulating Cathodic Antigen (POC-CCA) Test for the Detection of Schistosoma japonicum in Indonesia.

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Authors

GGunawanJPJoko PrastowoWNWisnu Nurcahyo

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Overview

Cross-sectional evaluation shows high specificity but low sensitivity of POC-CCA test for schistosomiasis in a community.

Key Points

  • This research aims to evaluate the effectiveness of a point-of-care circulating cathodic antigen test for diagnosing Schistosoma japonicum infection.
  • Community-based cross-sectional diagnostic evaluation among 226 residents in Central Sulawesi, Indonesia.
  • Stool samples examined using Kato-Katz technique as reference standard.
  • Urine samples tested using the POC-CCA cassette.
  • 36 participants (15.9%) were positive for S. japonicum by Kato-Katz, while only 6 (2.7%) were positive by POC-CCA.
  • Sensitivity of POC-CCA was 16.67% (95% CI: 6.37-32.81) and specificity was 98.95% (95% CI: 96.25-99.87).
  • Cohen's kappa coefficient was 0.246 (95% CI: 0.004-0.487), indicating fair agreement.

Cite This Study

Gunawan et al. (2026) studied this question.

synapsesocial.com/papers/69f19f16edf4b46824806328https://doi.org/10.4314/ejhs.v36i1.7
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