September 9, 2014European Heart JournalOpen Access

Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk

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Why the study?

Does electromechanical window negativity predict previous arrhythmic events in patients with genotyped long-QT syndrome?

Structured PICO

Does electromechanical window negativity predict previous arrhythmic events in patients with genotyped long-QT syndrome?

Population

244 patients with genotyped long-QT syndrome (LQTS), including 97 with previous arrhythmic events, and 76 matched healthy controls from three centers.

Intervention

Measurement of electromechanical window (EMW) non-invasively by continuous-wave echocardiography

Comparator

Healthy controls, and event-free LQTS patients

Outcome

Electromechanical window (EMW) duration and its association with previous arrhythmic eventssurrogate

Electromechanical window negativity is a strong, independent predictor of arrhythmic risk in patients with genotyped long-QT syndrome, offering incremental value over resting QTc.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support incremental LQTS risk stratification beyond QTc; leaves open prospective validation before clinical adoption.

Cite This Study

Bekke et al. (2014) studied this question.

synapsesocial.com/papers/69f1a08710fa38abb3d23639 https://doi.org/10.1093/eurheartj/ehu370

View Full Paper

Ask AI

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Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk

Structured PICO

Discussion

Implication

Cite This Study

Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider