November 15, 1979New England Journal of Medicine
Ventricular Fibrillation in the Wolff-Parkinson-White Syndrome
Why the study?
What are the clinical and electrophysiological risk factors for ventricular fibrillation in patients with Wolff-Parkinson-White syndrome?
Population
98 patients with Wolff-Parkinson-White syndrome
Design
Case-control
Authors
Discussion
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Member takes
Implication
AF history and rapid accessory pathway conduction associate with VF in WPW; hypothesis-generating and should not yet change practice.
Structured PICO
What are the clinical and electrophysiological risk factors for ventricular fibrillation in patients with Wolff-Parkinson-White syndrome?
P
Population
98 patients with Wolff-Parkinson-White syndrome (25 with a history of ventricular fibrillation related to preexcitation and 73 without this history)
O
Outcome
Electrophysiological characteristics and clinical history (prevalence of reciprocating tachycardia, atrial fibrillation, multiple accessory pathways, and R-R intervals during atrial fibrillation)
In patients with Wolff-Parkinson-White syndrome, a history of atrial fibrillation, reciprocating tachycardia, multiple accessory pathways, and rapid conduction over the accessory pathway are associated with increased susceptibility to ventricular fibrillation.
Cite This Study
Klein et al. (1979) studied this question.