Why the study?
Dyssynchrony persists in many patients despite conventional CRT, prompting evaluation of whether His bundle pacing and nonconventional configurations could achieve better electrical and mechanical resynchronization.
Do nonconventional modalities of cardiac resynchronization therapy using His bundle pacing improve electrical and mechanical dyssynchrony compared to conventional biventricular pacing in patients with CRT indications?
Population
20 patients with CRT indications
Comparison
CONV vs HBP alone vs HBP + CS vs TRIPLE pacing
Design
Acute intrapatient proof-of-concept comparison study
Authors
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May improve acute resynchronization metrics in CRT candidates; leaves open whether this improves long-term outcomes versus conventional BiV pacing.
Do nonconventional modalities of cardiac resynchronization therapy using His bundle pacing improve electrical and mechanical dyssynchrony compared to conventional biventricular pacing in patients with CRT indications?
Nonconventional CRT modalities incorporating His bundle pacing provide superior acute electrical and mechanical resynchronization compared to conventional biventricular pacing.
Coluccia et al. (2020) studied this question.
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