What question did this study set out to answer?

Compare simultaneously recorded central and peripheral arterial pressure pulses across conditions of rest, exercise, and head-up tilt.

November 1, 1955Circulation Research

Comparison of Simultaneously Recorded Central and Peripheral Arterial Pressure Pulses During Rest, Exercise and Tilted Position in Man

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Population

12 healthy subjects

Design

Cross-sectional

Authors

EKEdwin J. KroekerLahey Hospital and Medical Center EWEarl H. WoodWesleyan University

Discussion

Member takes

Implication

Radial pulse pressure overestimates central values by 46-65% across states; leaves open whether central estimates refine risk prediction in observational cohorts.

Key Points

Compare simultaneously recorded central and peripheral arterial pressure pulses across conditions of rest, exercise, and head-up tilt.
Simultaneously recorded central (aortic or subclavian), brachial, radial, and femoral arterial pressure pulses in 12 healthy subjects (N=12).
Recorded hemodynamics across three distinct physiological states: rest, exercise, and 70-degree head-up tilt.
Peripheral systolic pressure uniformly exceeded central systolic pressure generated by the identical heartbeat across subjects at rest.
Average radial pulse pressure was 146%, 146%, and 165% of central pulse pressure during rest, exercise, and 70-degree head-up tilt, respectively.
Radial mean arterial pressures measured 94%, 93%, and 98% of central mean pressures during rest, exercise, and tilt, respectively.

Structured PICO

Population

12 healthy subjects

Intervention

Simultaneous recording of central (aortic or subclavian), brachial, radial and femoral pressure pulses during conditions of rest, exercise and 70 degree head-up tilt

Outcome

Differences between central and peripheral arterial pressure pulsessurrogate

Peripheral systolic and pulse pressures significantly exceed central pressures across various physiological states, likely due to wave reflection and resonance effects.

Cite This Study

Kroeker et al. (1955) studied this question.

synapsesocial.com/papers/69f29d4a1b51e2fbf018751a https://doi.org/10.1161/01.res.3.6.623

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Implication

Radial pulse pressure overestimates central values by 46-65% across states; leaves open whether central estimates refine risk prediction in observational cohorts.

Comparison of Simultaneously Recorded Central and Peripheral Arterial Pressure Pulses During Rest, Exercise and Tilted Position in Man

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Comparison of Simultaneously Recorded Central and Peripheral Arterial Pressure Pulses During Rest, Exercise and Tilted Position in Man

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider