Population
16 anesthetized, autonomically blocked, atrially paced dogs
Comparison
Hemodynamic assessment using a time-varying… vs Baseline state before calcium infusion; normal…
Design
Preclinical
Authors
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Supports elastance modeling of LA inotropy in animals; leaves open translation to human hemodynamic adaptation.
In vivo left atrial contraction can be approximated by time-varying elastance, which is sensitive to inotropic changes and may help identify LA adaptation to chronic hemodynamic loads.
Hoit et al. (1994) studied this question.
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