Isolation of enniatins shows IC50 of 0.73 mg l–1 against 12-lipoxygenase, implying potential antimicrobial properties.
Cyclohexadepsipetides enniatin B, B1 and G were isolated from the cultivation broth of Fusarium dimerum Penzig, an endophyte of Magnolia x soulangeana. Their production was about 350 mg l–1 after 96 h of submerged cultivation in Sabouraud maltose medium. Isolated enniatins inhibited growth of selected microorganisms and activity of 12-lipoxygenase with IC50 = 0.73 mg l–1.
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Firáková et al. (2008) studied this question.
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