What question did this study set out to answer?

To characterize longitudinal biomarker changes in anti-CCP positive individuals and identify predictive markers for imminent inflammatory arthritis (IA).

April 30, 2026Lara D. Veeken

P102 Biomarker changes identify imminent inflammatory arthritis in anti-CCP positive at-risk individuals

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To characterize longitudinal biomarker changes in anti-CCP positive individuals and identify predictive markers for imminent inflammatory arthritis (IA).
Single-centre, prospective study with 543 anti-CCP positive participants.
Followed participants from initial symptoms until IA development.
Used multivariable panel logistic regression to identify IA predictors.
32.4% developed inflammatory arthritis within 12.1 months.
Increased early morning stiffness and ultrasound power Doppler signal marked imminent IA phase.
Four biomarkers identified as significant predictors for IA development within six months.

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Implication

Prospective study identifies biomarkers indicating imminent inflammatory arthritis in at-risk individuals, suggesting early intervention strategies.

Cite This Study

Duquenne et al. (2026) studied this question.

synapsesocial.com/papers/69f2a4da8c0f03fd67763f4f https://doi.org/10.1093/rheumatology/keag121.137

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Implication

Prospective study identifies biomarkers indicating imminent inflammatory arthritis in at-risk individuals, suggesting early intervention strategies.

P102 Biomarker changes identify imminent inflammatory arthritis in anti-CCP positive at-risk individuals

Key Points

Discussion

Implication

Cite This Study

P102 Biomarker changes identify imminent inflammatory arthritis in anti-CCP positive at-risk individuals

Key Points

Discussion

Implication

Cite This Study

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