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The research aims to review the latest diagnostic methods for tuberculosis (TB) and associated drug resistance detection.

Diagnostic Assays for TB Disease and Drug Resistance Detection—Advances and Latest WHO Recommendations

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The research aims to review the latest diagnostic methods for tuberculosis (TB) and associated drug resistance detection.
Discussion of nucleic acid amplification tests for active TB detection in pulmonary and extrapulmonary specimens.
Evaluation of rapid molecular assays and next-generation sequencing for early drug resistance identification.
Examination of traditional culture-based and phenotypic drug susceptibility testing for comprehensive profiling.
Nucleic acid amplification tests demonstrate improved accuracy for active TB diagnosis across specimen types.
Rapid molecular assays identify drug resistance effectively, enabling quicker treatment adjustments.
Integration of molecular and phenotypic methods is recommended for enhanced diagnostic capabilities.

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Diagnostic assays assess TB disease and resistance in various specimens, highlighting essential WHO recommendations.

Miotto et al. (2026) studied this question.

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