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April 1, 2026The Japanese Journal of Gastroenterological SurgeryOpen Access

A Case of AFP-Producing Gastric Cancer with Portal Vein Tumor Thrombosis That Was Radically Resected by Multidisciplinary Treatment

Yuya Hibino Satoshi KOBAYASHI Takehiro Takagi Takashi Maeda Takuya Mishina Shinji Kato Hiromitsu Kusunoki Yukihiro Shiraki

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Key Points

To evaluate the effectiveness of multidisciplinary treatment in the radical resection of AFP-producing gastric cancer with portal vein tumor thrombosis.
Patient diagnosed with advanced gastric cancer with portal vein thrombus.
Received 6 courses of CapeOX and nivolumab, followed by 3 additional courses of Capecitabine and nivolumab.
Underwent radical resection including total gastrectomy and portal vein resection after multiple therapies.
Pathology confirmed tumor stage as ypStage IIB with no tumor cells found in the portal vein post-surgery.
Post-operative follow-up of one year showed no recurrence of cancer.

Implication

Demonstrates effective radical resection of gastric cancer with portal vein thrombosis, suggesting multidisciplinary treatment is crucial.

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Cite This Study

Hibino et al. (2026) studied this question.

synapsesocial.com/papers/69f2f0e31e5f7920c6386e97 https://doi.org/10.5833/jjgs.2024.0107

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Keep reading

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1A Case of Ascending Colon Cancer with a Tumor Thrombosis in Superior Mesenteric Vein: Usefulness of CT Portography for Diagnosis of Intraluminal Tumor Thrombi in the Portal Vein Systemcase_report · 2009 · 4 citations
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3A case of locally advanced unresectable pancreatic cancer with pathologic complete response after conversion surgeryOriginal Research · 2026
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