A case of complete response to gemcitabine+nab-paclitaxel therapy for pleomorphic cell type anaplastic pancreatic cancer with liver metastasis

April 30, 2026Suizo

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Key Points

This case report aims to illustrate the effectiveness of gemcitabine and nab-paclitaxel therapy on anaplastic pancreatic cancer with liver metastasis.
Diagnosis was confirmed via ultrasound endoscopic fine-needle aspiration.
Aged 80 male patient received gemcitabine and nab-paclitaxel therapy for six cycles.
Follow-up imaging was conducted post-therapy to assess for tumor response.
Complete disappearance of primary tumor and liver metastases observed after six treatment cycles.
Grade 2 peripheral neuropathy noted during therapy, but overall the patient tolerated treatment well.
Patient remained free of recurrence for 7 years and 8 months after therapy cessation.

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Case report demonstrates complete response to therapy in an elderly male with liver metastasis, indicating potential treatment efficacy.

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Shionoya et al. (2026) studied this question.

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