Characterizing and Quantifying Mitral Annular Calcification for Patient-Predictive Modeling in the Era of TMVR

Sophia L. Alexis; Talal Alzahrani; Omar Khalique; Annapoorna Kini; Samin K. Sharma; George Dangas; Rebecca T. Hahn; Susheel Kodali; Martin B. Leon; David Adams; Isaac George; Gilbert Tang

doi:10.1016/s0735-1097(20)31740-x

March 1, 2020Journal of the American College of Cardiology

Characterizing and Quantifying Mitral Annular Calcification for Patient-Predictive Modeling in the Era of TMVR

View at Publisher

Ask AI

Bookmark

Share

Why the study?

A systematic approach to quantifying mitral annular calcification is essential to determine feasibility of TMVR, prompting an effort to standardize MAC classification to guide therapy.

Key Points

This study aims to standardize the classification of mitral annular calcification to improve decision-making for transcatheter mitral valve replacement.
Evaluated 87 patients from 9/2015 to 7/2019 across 2 centers
Conducted CT analysis to assess mitral annular calcification
Developed a standardized classification system for MAC
Quantified levels of mitral annular calcification in 87 patients
Established a reliable predictive model for TMVR outcomes
Provided a framework for therapy guidance based on MAC severity

Structured PICO

P

Population

87 patients who underwent CT analysis from 9/2015 to 7/2019 at 2 centers

I

Intervention

CT analysis for characterizing and quantifying mitral annular calcification (MAC)

O

Outcome

Evaluation of mitral annular calcification (abstract truncated)surrogate

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Quantifies mitral annular calcification to predict outcomes in patients, suggesting improved therapy guidance.

Abstract

A systematic approach to quantifying mitral annular calcification (MAC) is essential to determine feasibility of transcatheter mitral valve replacement (TMVR). We aim to standardize MAC classification to guide therapy. 87 patients from 9/2015-7/2019 underwent CT analysis at 2 centers to evaluate

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Alexis et al. (2020) studied this question.

synapsesocial.com/papers/69f41ba5ef2b80c36f936af5 https://doi.org/10.1016/s0735-1097(20)31740-x

View at Publisher

Ask AI

Bookmark

Share

Characterizing and Quantifying Mitral Annular Calcification for Patient-Predictive Modeling in the Era of TMVR

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Characterizing and Quantifying Mitral Annular Calcification for Patient-Predictive Modeling in the Era of TMVR

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading