Why the study?
Does tight systolic blood pressure control (<130 mm Hg) improve cardiovascular outcomes compared to usual control (130-<140 mm Hg) in patients with diabetes and coronary artery disease?
Population
6,400 patients aged at least 50 years with diabetes and coronary artery disease, multinational.
Comparison
Tight systolic blood pressure control achieved… vs Usual systolic blood pressure control and…
Design
Cohort
Follow-up
16,893 patient-years
Authors
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Does not support tight SBP control in diabetes with CAD; leaves open optimal targets for randomized trials.
Does tight systolic blood pressure control (<130 mm Hg) improve cardiovascular outcomes compared to usual control (130-<140 mm Hg) in patients with diabetes and coronary artery disease?
Tight systolic blood pressure control (<130 mm Hg) in patients with diabetes and coronary artery disease does not improve cardiovascular outcomes compared to usual control (130-<140 mm Hg) and may increase long-term mortality.
Cooper‐DeHoff et al. (2010) studied this question.
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