DQIS — Register of Scientific Objections v3.0

Supplementary document to the DQIS framework (Zenodo DOI: 10.5281/zenodo.19855263). Register of scientific objections identified during preparation for academic validation of the DQIS framework — Distributed Quantum-Inspired Immune Surveillance. For each objection: precise formulation, severity assessment, mathematical and biological analysis, empirical data from the literature, and defensible response. Version 3.0 — 6 objections addressed: O1 — Empirical grounding of parameter p_i (with per-channel proxies from literature + technical feasibility of sensors) O2 — Statistical independence of channels (resolved with balanced group quorum) O3 — Selective pressure at population scale (explicit calculation + τ_i update mechanism) O4 — Channel T-ε: reachability of p_i = 0.01 O5 — DQIS-J: number of paediatric procedures O6 — T-γ* temporal criterion (>30 min) vs T-lymphocyte contact time (resolved with NFAT-like temporal integration) Not a peer-reviewed publication. Prior art deposit.