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This study examines how the fungicide difenoconazole and herbicide tebuthiuron affect Aedes aegypti larvae's survival, behavior, and protein expression.

May 1, 2026

Independent Exposure to the Fungicide Difenoconazole or the Herbicide Tebuthiuron Disrupts Survival, Behavior, and Alters Midgut-Associated Protein Detection in Aedes aegypti Larvae.

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Authors

FMFranciane Rosa MirandaUniversidade Federal de Viçosa VRVinícius Cordeiro RochaUniversidade Federal de Viçosa CFCliver Fernandes Farder-GomesUniversidade Federal de Viçosa

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Implication

Independent exposure to difenoconazole and tebuthiuron disrupts survival and alters midgut proteins in Aedes aegypti larvae, highlighting ecological impacts.

Key Points

This study examines how the fungicide difenoconazole and herbicide tebuthiuron affect Aedes aegypti larvae's survival, behavior, and protein expression.
Larvae were exposed to difenoconazole and tebuthiuron to assess changes in behavior and enzyme levels.
Enzymatic assays measured antioxidant enzyme activity and midgut protein expression.
Immunolabeling techniques identified changes in specific midgut-associated proteins.
Difenoconazole decreased larval activity, while tebuthiuron increased it.
Key antioxidant enzymes showed reduced activity with chemical exposure, affecting redox homeostasis.
Exposure to difenoconazole increased markers of apoptosis and autophagy, indicating cellular stress.

Cite This Study

Miranda et al. (2026) studied this question.

synapsesocial.com/papers/69f44420967e944ac55671b2 https://doi.org/10.1002/jat.70219

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Implication

Independent exposure to difenoconazole and tebuthiuron disrupts survival and alters midgut proteins in Aedes aegypti larvae, highlighting ecological impacts.

Independent Exposure to the Fungicide Difenoconazole or the Herbicide Tebuthiuron Disrupts Survival, Behavior, and Alters Midgut-Associated Protein Detection in Aedes aegypti Larvae.

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Key Points

Cite This Study

Independent Exposure to the Fungicide Difenoconazole or the Herbicide Tebuthiuron Disrupts Survival, Behavior, and Alters Midgut-Associated Protein Detection in Aedes aegypti Larvae.

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