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April 23, 2026

Annexin A5 Regulates Store-Operated Calcium Entry via Glyceraldehyde-3-Phosphate Dehydrogenase in Hepatocellular Carcinoma.

Weicheng Gao X H Zhang Shuai Ma Feifei Wu Xingguo Zhong

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Key Points

The study investigates how Annexin A5 affects store-operated calcium entry and tumor growth in hepatocellular carcinoma (HCC).
Experiments were conducted to silence ANXA5 and assess its impact on tumor growth.
Expression levels of Ki-67, vimentin, and CD206 were measured to evaluate tumor characteristics.
ANXA5 silencing significantly inhibited tumor growth.
Reduced expression of Ki-67, vimentin, and CD206 was observed, indicating a potential effect on tumor marker expression.

Implication

Explores the effect of ANXA5 silencing on tumor growth in hepatocellular carcinoma, highlighting its therapeutic potential.

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Cite This Study

Gao et al. (2026) studied this question.

synapsesocial.com/papers/69f4443a967e944ac55673ec https://doi.org/10.31083/fbl49504

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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5Clinical Significance of Annexin A4 as a Biomarker in the Early Diagnosis of Hepatocellular CarcinomaCohort Study · 2020 · 12 citations